The spatial and temporal expression pattern of sevenless is exclusively controlled by gene-internal elements

摘要: The sevenless gene controls the fate of a single photoreceptor cell type in developing eye Drosophila. Its RNA and protein accumulate transiently subpopulation cells imaginal disc. We have used P-element transformation with different minigenes marker constructs to identify cis-acting regulatory regions required for complex expression pattern. Our results indicate that upstream region is devoid any detectable elements sequences located 3' transcription start site are sufficient promote These gene-internal function both orientations on heterologous promoters, also when placed at end lacZ reporter gene.