Can sildenafil treat primary premature ejaculation? A prospective clinical study.

摘要: Recently sildenafil has been demonstrated to be effective in treating premature ejaculation (PE). However these studies ignored female factors and could not exclude the probability of drug interaction when combined with paroxetine. Therefore aim this study was evaluate efficacy safety alone treatment primary PE taking into consideration. One hundred eighty potent men were randomly divided three groups followed up for 6 months. Group A treated 50 mg as needed group B 20 paroxetine daily C squeeze technique daily. Intravaginal ejaculatory latency time (IELT) grade intercourse satisfactory score (ISS) frequency adverse effects drugs recorded before 3 months after treatment. Compared pretreatment had significant differences all parameters or except (all P = 0.00). there no between After 1.7% 18.3% 36.7% patients respectively withdrew from 86.7% 60.0% 45.0% wanted further original administration statistically (both Sildenafil is very safe treat much higher than technique. (authors)