作者: Nawel Meskine , Marie-Pierre Vullierme , Magaly Zappa , Gaspard d’Assignies , Annie Sibert
DOI: 10.1016/J.ACRA.2011.01.025
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摘要: Rationale and Objectives Percutaneous liver biopsy for tumors performed under local anesthesia is still a painful procedure. The aim of this study was to evaluate the patient’s reaction analgesic efficacy safety an equimolar mixture oxygen nitrous oxide (EMONO) inhalation. Materials Methods A monocenter, prospective, randomized double-blind controlled including 99 adult patients undergoing ultrasound tumors. 50 received EMONO 49 placebo. Pain evaluated by before after procedure using Visual Analog Scale. Results Analgesic control, defined difference between final initial VAS scores (Δ), significantly better in group than placebo (Δ = 17.8 ± 25.5 mm vs 30.1 32.6 mm; P .045. number who would agree undergo another same conditions higher (92.0% 75.5%, .026). There were no side-effects from administration EMONO. Conclusion This shows that receiving had control percutaneous focal lesions group. Moreover, acceptance additional biopsies