No cognitive deficits in men formerly exposed to lead

摘要: OBJECTIVES: The objective of the study was to investigate long-term cognitive effects resulting from low moderate lead exposure below current threshold values. Executive functions, attention, visuospatial and visuomotor functioning in workers formerly exposed were investigated. METHODS: 48 men with a mean blood level (PbB) 5.4 μg Pb/100 ml investigated, together matched controls (PbB, 4.7 ml) out pool 61 males. two groups for age, years spent education, verbal intelligence gram alcohol consumption per week. following neuropsychological tests used: modified Wisconsin card sorting test, block design visual recognition simple reaction time, choice digit–symbol substitution. Lead assessed using both cumulative measurements. RESULTS: There no significant differences parameters between groups. When analyzing dose–response relationships, negative correlations found PbB performance scores substitution tests. High (IBL, >5000; duration exposure, >5 years) correlated only wrong reactions test. CONCLUSIONS: results our indicate that deficits low-level are reversible. limited (all values always 55 ml), extrapolation these persons heavily is not possible.