Lead in bone. IV. Distribution of lead in the human skeleton.

摘要: Flameless atomic absorption spectroscopy was used to measure lead concentrations in samples from 5 selected human skeletal sites (tibia, skull, rib, ilium, and vertebra) obtained 134 hospital autopsies. Lead distributed unequally among the different bones distinct patterns that were age-, some extent, sex-dependent. To estimate concentration of entire skeleton, all divided into groups based on their approximate compact/trabecular bone ratios, considering each our sampled be prototype for such group. Regression analysis 10 possible site pair values at ages yielded age-related constants. These constants incorporated an equation we developed can both mean (Pb) body skeleton also predict any other 4 if 1 is measured. Applications these data vivo measurements are detailed with respect selection measured, estimation total burden, anticipated variations or error, dependence factors age sex population.