Telemetric Blood Pressure Monitoring in Conscious Rats Before and After Compression Injury of Spinal Cord
作者： Dmitry N. Mayorov , Michael A. Adams , Andrei V. Krassioukov
DOI: 10.1089/089771501750357663
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摘要: Abnormal cardiovascular control after spinal cord injury (SCI) results in hypotension soon injury. Later, paroxysmal hypertension and bradycardia response to sensory stimulation below the level of develop most people with SCI. In this study, we used a radiotelemetry system, rats (n = 7), investigate effect clinically relevant compression model SCI at T5 segment on mean arterial pressure (MAP) heart rate (HR) rest colorectal distension. The transducers were implanted 1 month before clip (50-g) continuous recording MAP HR was established for period 2.5 months. associated (86 ± 3 mm Hg) day following 2 days, gradually returned preinjury levels. By contrast, increased remained unchanged thereafter. Three days SCI, distension caused an increase 8 Hg accompanied by (-18 bpm). One ...
liebertonline.com参考文章(23)
Tator Ch, Rivlin As, Effect of duration of acute spinal cord compression in a new acute cord injury model in the rat. Surgical Neurology. ,vol. 10, pp. 38- 43 ,(1978)
Daniel R. Marsh, Sharon T. Wong, Susan O. Meakin, James I. S. MacDonald, Eilis F. Hamilton, Lynne C. Weaver, Neutralizing intraspinal nerve growth factor with a trkA-IgG fusion protein blocks the development of autonomic dysreflexia in a clip-compression model of spinal cord injury. Journal of Neurotrauma. ,vol. 19, pp. 1531- 1541 ,(2002) , 10.1089/089771502762300201
Robert Reuven Sokal, F. James Rohlf, Biometry: The Principles and Practice of Statistics in Biological Research ,(1969)
Junichi Kameyama, Masaharu Kanazawa, Tohru Nunokawa, Norio Moriai, Kaoru Yoshinaga, Masanori Munakata, Circadian blood pressure rhythm in patients with higher and lower spinal cord injury: simultaneous evaluation of autonomic nervous activity and physical activity. Journal of Hypertension. ,vol. 15, pp. 1745- 1749 ,(1997) , 10.1097/00004872-199715120-00083
Michelle K. Bazil, Christine Krulan, Randy L. Webb, Telemetric Monitoring of Cardiovascular Parameters in Conscious Spontaneously Hypertensive Rats Journal of Cardiovascular Pharmacology. ,vol. 22, pp. 897- 905 ,(1993) , 10.1097/00005344-199312000-00019
A.V. Krassioukov, L.C. Weaver, Morphological changes in sympathetic preganglionic neurons after spinal cord injury in rats. Neuroscience. ,vol. 70, pp. 211- 225 ,(1996) , 10.1016/0306-4522(95)00294-S
Andrei V. Krassioukov, Devin G. Johns, Lawrence P. Schramm, Sensitivity of sympathetically correlated spinal interneurons, renal sympathetic nerve activity, and arterial pressure to somatic and visceral stimuli after chronic spinal injury. Journal of Neurotrauma. ,vol. 19, pp. 1521- 1529 ,(2002) , 10.1089/089771502762300193
Andrei V. Krassioukov, Lynne C. Weaver, Reflex and Morphological Changes in Spinal Preganglionic Neurons After Cord Injury in Rats Clinical and Experimental Hypertension. ,vol. 17, pp. 361- 373 ,(1995) , 10.3109/10641969509087077
Michael G. Fehlings, Charles H. Tator, The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury. Experimental Neurology. ,vol. 132, pp. 220- 228 ,(1995) , 10.1016/0014-4886(95)90027-6
N.R Krenz, L.C Weaver, Sprouting of primary afferent fibers after spinal cord transection in the rat. Neuroscience. ,vol. 85, pp. 443- 458 ,(1998) , 10.1016/S0306-4522(97)00622-2