Sequence and Organization of the Left Multigene Family 110 Region of the Vero-adapted L60V Strain of African Swine Fever Virus
作者： Sandra Pires , Grac˜a Ribeiro , Joa˜o V. Costa
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摘要: Sequencing of the left variable region L60V Vero cell-adapted strain African swine fever virus (ASFV) showed presence three genes belonging to multigene family 110 (MGF110) and a fourth unrelated gene. This gene was separated from MGF110 by rich in direct repeats. The first gene, V1L, with 104 codons, only moderately related other two, W1L W2L, 124 80 respectively. These two were closely related, W2L being truncated duplication W1L. Homology matrix analysis sequence against itself existence repeated block corresponding central conserved domain genes, flanked blocks W2L. comparison organization ASFV that field isolates adapted viruses revealed adaptation resulted similar large deletions map, their right boundaries, exactly at same positions intergenic repeat-rich region.
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S. Vydelingum, S. A. Baylis, C. Bristow, G. L. Smith, L. K. Dixon, Duplicated genes within the variable right end of the genome of a pathogenic isolate of African swine fever virus Journal of General Virology. ,vol. 74, pp. 2125- 2130 ,(1993) , 10.1099/0022-1317-74-10-2125
Enrique Tabares, Isabel Olivares, G Santurde, Maria Jose Garcia, Elisabeth Martin, ME Carnero, African swine fever virus DNA: deletions and additions during adaptation to growth in monkey kidney cells. Archives of Virology. ,vol. 97, pp. 333- 346 ,(1987) , 10.1007/BF01314431
Rafael Blasco, Inmaculada de la Vega, Fernando Almazan, Montserrat Aguero, Eladio Viñuela, Genetic variation of african swine fever virus: Variable regions near the ends of the viral DNA Virology. ,vol. 173, pp. 251- 257 ,(1989) , 10.1016/0042-6822(89)90241-9
Rafael Blasco, Montserrat Agüero, JoséM. Almendral, Eladio Viñuela, Variable and constant regions in african swine fever virus DNA Virology. ,vol. 168, pp. 330- 338 ,(1989) , 10.1016/0042-6822(89)90273-0
T. Yozawa, G.F. Kutish, C.L. Afonso, Z. Lu, D.L. Rock, Two Novel Multigene Families, 530 and 300, in the Terminal Variable Regions of African Swine Fever Virus Genome Virology. ,vol. 202, pp. 997- 1002 ,(1994) , 10.1006/VIRO.1994.1426
Inmaculada De La Vega, Eladio Viñuela, Rafael Blasco, Genetic variation and multigene families in African swine fever virus. Virology. ,vol. 179, pp. 234- 246 ,(1990) , 10.1016/0042-6822(90)90293-Z
John Devereux, Paul Haeberli, Oliver Smithies, A comprehensive set of sequence analysis programs for the VAX Nucleic Acids Research. ,vol. 12, pp. 387- 395 ,(1984) , 10.1093/NAR/12.1PART1.387
Alexandra Martins, Graça Ribeiro, M. Isabel Marques, JoãSo V. Costa, Genetic identification and nucleotide sequence of the DNA polymerase gene of African swine fever virus Nucleic Acids Research. ,vol. 22, pp. 208- 213 ,(1994) , 10.1093/NAR/22.2.208
Ronald D. Wesley, Ann E. Tuthill, Genome relatedness among African swine fever virus field isolates by restriction endonuclease analysis Preventive Veterinary Medicine. ,vol. 2, pp. 53- 62 ,(1984) , 10.1016/0167-5877(84)90048-5
Antonio González, Antonio Talavera, José M. Almendral, Eladio Viñuela, Hairpin loop structure of African swine fever virus DNA Nucleic Acids Research. ,vol. 14, pp. 6835- 6844 ,(1986) , 10.1093/NAR/14.17.6835