Identifying environmental chemicals causing mutations and cancer

摘要: Damage to DNA appears be the major cause of most cancer and genetic birth defects may contribute aging heart disease as well. The agents that this damage must identified. Many these are natural chemicals present in human diet complex mixtures. tens thousands man-made have been introduced into environment last few decades also tested for their ability DNA. Existing animal tests epidemiology alone inadequate task because time, expense, difficulty dealing with mixtures, Newly developed short-term tests, them assaying mutagenicity, discussed key tools identifying environmental mutagens carcinogens.