Use of Ibuprofen in Unusual Circumstances

摘要: The clinical pharmacology of ibuprofen (Motrin, Upjohn) in relation to the pathophysiologic aspects various diseases is explained. An understanding prostaglandin's numerous effects can help clinician expand use (as Barttern's syndrome) and exercise caution as warranted, when treating patients with renal disease. Knowledge ibuprofen's may also enable practitioners prescribe drug rationally situations not weil represented litereature, elderly or individuals bleeding diatheses severe liver multiple-drug therapy aspirin, warfarin, phenytoin, digoxin, lithium explored. Perusal literature enables gain an awareness patient subpopulations warranting careful medication, including systemic lupus erythematosus, mixed connective tissue disease, aspirin-induced asthma.