Role of Astrocytes in Neurovascular Coupling
作者： Gabor C. Petzold , Venkatesh N. Murthy
DOI: 10.1016/J.NEURON.2011.08.009
关键词:
摘要: Neural activity is intimately tied to blood flow in the brain. This coupling specific enough space and time that modern imaging methods use local hemodynamics as a measure of brain activity. In this review, we discuss recent evidence indicating neuronal coupled changes through an intermediary, astrocyte. We highlight unresolved issues regarding role astrocytes propose ways address them using novel techniques. Our focus on cellular level analysis in vivo, but also relate mechanistic insights gained from ex vivo experiments native tissue. review some strategies harness advances optical genetic study neurovascular intact
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