Proteazy serynowe i ich klasyfikacja według systemu merops

作者: Paweł Nowak , Michał Błażej Ponczek , Michał Bijak

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摘要: Proteolytic enzymes, known also as the proteases, proteinases or peptidases, belong to class of hydrolases involved in hydrolytic degradation peptide bonds. These enzymes have been identified both prokaryotic and eukaryotic cells. Typical human genome contains about 2% genes that are responsible for encoding proteolytic enzymes. Serine proteases represent almost one-third all The name these is derived from presence nucleophilic amino acid: serine located active site enzyme, which attacks carbonyl group bond forming thereby an intermediate called acyl-enzyme. Due fact reactions catalyzed by very complex Rawlings Barrett proposed a high precision classification system MEROPS. Under this system, divided into clans families. recent MEROPS database 15 containing together 53 aim paper short description their division different clans.

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