作者: Héctor F. Escobar-Morreale , José L. San Millán
DOI: 10.1016/J.TEM.2007.07.003
关键词:
摘要: Abdominal adiposity, overweightness and obesity are frequently present in patients with polycystic ovary syndrome (PCOS). A large body of evidence suggests that abdominal adiposity the resulting insulin resistance contribute to ovarian and, possibly, adrenal hyperandrogenism. However, androgen excess itself might also fat deposition hyperandrogenic women. Recent genomic proteomic analyses visceral from PCOS have detected differences gene expression protein content compared those non-hyperandrogenic Here we review existing for a vicious circle whereby favoring further facilitates secretion by ovaries adrenals patients.