Consolidative Proton Therapy Following High-dose Chemotherapy and Autologous Stem Cell Transplant in an Adolescent with Relapsed Hodgkin Lymphoma.
作者： Nicholas B. Figura , Stella Flampouri , Keri Hopper , Robert B. Marcus , Nancy P. Mendenhall
关键词:
摘要: We present a case of an adolescent male with relapsed Hodgkin lymphoma involving the mediastinum two years following chemotherapy without radiotherapy. The patient was treated second-line followed by high-dose and autologous stem cell transplant then presented for evaluation consolidative involved-field proton therapy (PT). Comparative treatment plans were developed three-dimensional X-ray radiotherapy (3DXRT) PT. PT substantially reduced dose to lungs, heart, esophagus, total body compared 3DXRT, resulting in should reduce risk late side effects including secondary malignancies cardiovascular disease.
sci-hub.se 参考文章(9)
Hans Theodor Eich, Uwe Haverkamp, Andreas Engert, Martin Kocher, Roman Skripnitchenko, Corinne Brillant, Susanne Sehlen, Eckhart Dühmke, Volker Diehl, Rolf-Peter Müller, Biophysical analysis of the acute toxicity of radiotherapy in Hodgkin's lymphoma--a comparison between extended field and involved field radiotherapy based on the data of the German Hodgkin Study Group. International Journal of Radiation Oncology Biology Physics. ,vol. 63, pp. 860- 865 ,(2004) , 10.1016/J.IJROBP.2005.02.053
D. A Mulrooney, M. W Yeazel, T. Kawashima, A. C Mertens, P. Mitby, M. Stovall, S. S Donaldson, D. M Green, C. A Sklar, L. L Robison, W. M Leisenring, Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: retrospective analysis of the Childhood Cancer Survivor Study cohort. BMJ. ,vol. 339, pp. 34- 34 ,(2009) , 10.1136/BMJ.B4606
Merideth M. M. Wendland, Julie D. Asch, Michael A. Pulsipher, John W. Thomson, Dennis C. Shrieve, David K. Gaffney, The impact of involved field radiation therapy for patients receiving high-dose chemotherapy followed by hematopoietic progenitor cell transplant for the treatment of relapsed or refractory Hodgkin disease. American Journal of Clinical Oncology. ,vol. 29, pp. 189- 195 ,(2006) , 10.1097/01.COC.0000209370.61355.8E
Lois B Travis, Mary Gospodarowicz, Rochelle E Curtis, E Aileen Clarke, Michael Andersson, Bengt Glimelius, Timo Joensuu, Charles F Lynch, Flora E Van Leeuwen, Eric Holowaty, Hans Storm, Ingrid Glimelius, Eero Pukkala, Marilyn Stovall, Joseph F Fraumeni Jr, John D Boice Jr, Ethel Gilbert, Lung Cancer Following Chemotherapy and Radiotherapy for Hodgkin's Disease Journal of the National Cancer Institute. ,vol. 94, pp. 182- 192 ,(2002) , 10.1093/JNCI/94.3.182
Shannon Kahn, Christopher Flowers, Zhiheng Xu, Natia Esiashvili, Does the Addition of Involved Field Radiotherapy to High-Dose Chemotherapy and Stem Cell Transplantation Improve Outcomes for Patients With Relapsed/Refractory Hodgkin Lymphoma? International Journal of Radiation Oncology*Biology*Physics. ,vol. 81, pp. 175- 180 ,(2011) , 10.1016/J.IJROBP.2010.05.010
Karyn A. Goodman, Elyn Riedel, Victoria Serrano, Subhash Gulati, Craig H. Moskowitz, Joachim Yahalom, Long-Term Effects of High-Dose Chemotherapy and Radiation for Relapsed and Refractory Hodgkin's Lymphoma Journal of Clinical Oncology. ,vol. 26, pp. 5240- 5247 ,(2008) , 10.1200/JCO.2007.15.5507
Markhaba Tukenova, Catherine Guibout, Odile Oberlin, Françoise Doyon, Abdeddahir Mousannif, Nadia Haddy, Sylvie Guérin, Hélène Pacquement, Albertine Aouba, Mike Hawkins, Dave Winter, Jean Bourhis, Dimitri Lefkopoulos, Ibrahima Diallo, Florent de Vathaire, Role of Cancer Treatment in Long-Term Overall and Cardiovascular Mortality After Childhood Cancer Journal of Clinical Oncology. ,vol. 28, pp. 1308- 1315 ,(2010) , 10.1200/JCO.2008.20.2267
A. C. Mertens, Q. Liu, J. P. Neglia, K. Wasilewski, W. Leisenring, G. T. Armstrong, L. L. Robison, Y. Yasui, Cause-Specific Late Mortality Among 5-Year Survivors of Childhood Cancer: The Childhood Cancer Survivor Study Journal of the National Cancer Institute. ,vol. 100, pp. 1368- 1379 ,(2008) , 10.1093/JNCI/DJN310
Vassilios Papadakis, Charlotte Tan, Glenn Heller, Charles Sklar, Growth and final height after treatment for childhood Hodgkin disease. Journal of Pediatric Hematology Oncology. ,vol. 18, pp. 272- 276 ,(1996) , 10.1097/00043426-199608000-00007