The effects of pre-pregnancy BMI and maternal factors on the timing of adiposity rebound in offspring

摘要: Objective To assess the effect of pre-pregnancy body mass index (BMI), gestational weight gain (GWG), and other maternal factors on timing adiposity rebound (AR). Methods In this study, 594 mothers (mothers who do not have diabetes underweight) from longitudinal Growth Obesity Chilean Cohort Study self-reported their weights at beginning end pregnancies, heights were measured. Pre-pregnancy BMI was categorized as normal weight, overweight, or obesity, GWG assessed according to Institute Medicine guidelines. For children, height measurements 0 3 years retrieved records, they measured age 4 7 years. curves used estimate AR, which early ( years). The associations between AR tested using logistic regression models. Results In total, 33% had excess 31.2% exceeded recommendations, 45% children AR. parity associated with earlier (OR = 1.07, 95% CI = 1.02-1.11; OR = 0.86; CI = 0.74-0.99, respectively), but unrelated. Conclusions These results suggest that preventive strategies for promoting BMI, especially in women's first could delay protective metabolic effects offspring.