Non-natural semaphorins 3 and their medical use
作者： Luca Tamagnone , Enrico Giraudo , Guido Serini
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摘要: The present invention relates to non-naturally occurring, mutated Semaphorin 3 molecules. Particularly, the or functional fragment thereof that exhibit improved properties and pharmacologic effects, e.g., in treatment of angiogenic disease cancer. In addition, nucleic acid molecules encoding such polypeptides, vectors hosts comprising acids. further methods for producing polypeptides invention, using them disease, particular medical intervention diseases, tumors and/or
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