Absence of intravascular bubble nucleation in dead rats

摘要: Bubble formation in the inferior vena cavae (IVC) of dead rats was investigated after 6-15-h exposures to air at 123 atm abs (12.5 MPa) and decompression 1 13.6 atm/min (1.4 MPa/min). The maximum estimated air-supersaturation attained IVCs 6.1-18.3 (0.6-1.8 MPa). Bubbles were detected by light microscopy, buoyancy, underwater dissection. No bubbles formed 42 blood-filled that isolated from circulation ligatures, but always observed unisolated (P < 0.000005). Other filled with tap water, water bubbles, or iron filings. 13% 16% containing preexisting 80% Results indicate supersaturations a) blood is resistant de novo bubble formation; b) are dissolved compression; c) originate gas nuclei; d) filings harbor nuclei able survive 122 (12.4 overpressures form on subsequent decompression.