The spectrum of pediatric tumors in infancy, childhood, and adolescence: a comprehensive review with emphasis on special techniques in diagnosis.

摘要: The spectrum of pediatric tumors varies considerably, from those derived blastemal cells in various organ systems to proliferations soft tissue supporting hamartomatous processes that mimic malignant tumors. Small round cell are often undifferentiated or poorly differentiated, making it difficult sometimes provide a definitive diagnosis. Both benign and require coordinated method for diagnosis, need comprehensive evaluation the most appropriate diagnosis designing therapy predicting prognosis. Pediatric integration routine histopathologic examination with histochemical, immunocytochemical, ultrastructural, cytogenetic, diagnostic molecular pathology techniques. This review provides updated guidelines respect application these special techniques this rapidly evolving arena.