Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization

作者: K. Lee , H. Zhang , D. Z. Qian , S. Rey , J. O. Liu

DOI: 10.1073/PNAS.0909353106

关键词:

摘要: … directly to HIF-1 and HIF-2 and inhibits HIF-1 dimerization … blood, and tumor vascularization. These results provide proof of principle that small molecules can inhibit dimerization of HIF-1 …

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