摘要: • Neonates with necrotizing tracheobronchitis present a diverse clinical spectrum from asymptomatic disease to severe airway obstruction. A retrospective clinicopathologic study of 206 neonatal autopsy reports spanning three-year period yielded 122 cases an incidence 59%. All patients received treatment prior the development high-frequency ventilator jet, oscillator, or interruption. The site and submucosal depth involvement was variable. most commonly affected anatomic middle thoracic trachea (56%). common cause identified ischemia mucosa submucosa, occurring profound birth asphyxia and/or shock. presence supports concept that decreased tracheoperfusion may be important factor in tracheobronchial abnormalities. ( AJDC 1988;142:1094-1098)
sci-hub.se 参考文章(20)
Patrick K. Lewallen, Mark C. Mammel, Stephen J. Boros, Margaret J. Gordon, Marylyn C. Sutton, Janice P. Ophoven, High-frequency ventilation and tracheal injuries. Pediatrics. ,vol. 77, pp. 608- 613 ,(1986)
Paul S. Symchych, Marcel Cadotte, Squamous metaplasia and necrosis of thetrachea complicating prolonged nasotracheal intubation of small newborn infants The Journal of Pediatrics. ,vol. 71, pp. 534- 541 ,(1967) , 10.1016/S0022-3476(67)80104-5
Joseph J. Volpe, Neurology of the Newborn ,(1981)
Juan L. Sotomayor, Large-Airway Collapse due to Acquired Tracheobronchomalacia in Infancy Archives of Pediatrics & Adolescent Medicine. ,vol. 140, pp. 367- 371 ,(1986) , 10.1001/ARCHPEDI.1986.02140180101035
Itzhak Brook, William J. Martin, Sydney M. Finegold, Bacteriology of tracheal aspirates in intubated newborn. Chest. ,vol. 78, pp. 875- 877 ,(1980) , 10.1378/CHEST.78.6.875
Robert W. Miller, Peak Woo, Robert K. Kellman, Terri S. Slagle, Tracheobronchial abnormalities in infants with bronchopulmonary dysplasia The Journal of Pediatrics. ,vol. 111, pp. 779- 782 ,(1987) , 10.1016/S0022-3476(87)80267-6
Stephen J. Boros, Mark C. Mammel, Patrick K. Lewallen, J. Michael Coleman, Margaret J. Gordon, Janice Ophoven, Necrotizing tracheobronchitis: a complication of high-frequency ventilation. The Journal of Pediatrics. ,vol. 109, pp. 95- 100 ,(1986) , 10.1016/S0022-3476(86)80585-6
Reese H. Clark, Thomas E. Wiswell, Donald M. Null, Robert A. deLemos, Jacqueline J. Coalson, Tracheal and bronchial injury in high-frequency oscillatory ventilation compared with conventional positive pressure ventilation The Journal of Pediatrics. ,vol. 111, pp. 114- 118 ,(1987) , 10.1016/S0022-3476(87)80356-6
Leon A. Metlay, Trevor A. Macpherson, Nalini Doshi, J. Ross Milley, Necrotizing tracheobronchitis in intubated newborns: a complication of assisted ventilation. Pediatric pathology / affiliated with the International Paediatric Pathology Association. ,vol. 7, pp. 575- 584 ,(1987) , 10.3109/15513818709161421
HARESH KIRPALANI, TOM HIGA, MAX PERLMAN, JACK FRIEDBERG, ERNEST CUTZ, Diagnosis and therapy of necrotizing tracheobronchitis in ventilated neonates. Critical Care Medicine. ,vol. 13, pp. 792- 797 ,(1985) , 10.1097/00003246-198510000-00004