Diagnosis of Tracheal Injury in Mechanically Ventilated Premature Infants by Flexible Bronchoscopy

摘要: Flexible bronchoscopy (FB) is uniquely suited for the study of large airway lesions in ventilated premature infant. However, no standardized clinical scoring system distal tracheal injury exists and adverse consequences FB infants are not well described. Using a prototype Olympus fiberoptic ultrathin bronchoscope with directable tip an outer diameter 2.2 mm, we serially scored conventionally on basis mucosal obstructive changes observed at bronchoscopy. In addition, prospectively evaluated incidence cardiovascular pulmonary effects during, immediately after, within 1 h FB. We performed 21 FBs eight birth weight 1,239±438 g gestational age 30±3 weeks. The carina mainstem bronchi were easily visualized all using bronchoscope. During first several days life, moderate-to-severe occurred frequently, while infrequently. Distal appeared to improve during fourth week life. Mild began appear second Adverse our patient population included transient hypoxemia bradycardia FB, systolic blood pressure after emesis Serious or observed. conclude that can be safely appropriate monitoring useful tool assessment serial evaluation infants. speculate moderateto-severe may associated development later injury. On this preliminary study, further prospective investigations warranted.