T-2 tetraol is cytotoxic to a chicken macrophage cell line

作者: MT Kidd , MA Qureshi , WM Hagler , R Ali

DOI: 10.1093/PS/76.2.311

关键词:

摘要: Cytotoxic effects of T-2 tetraol, a toxin derivative, on the MQ-NCSU chicken macrophage cell line were quantified by direct in vitro exposure. Macrophage cultures exposed to 1, 10, 20, 40, 80, 160, and 320 micrograms/mL tetraol for 1 h. viability after exposure tetraol. was reduced increasing concentrations (linear effect, P < or = 0.001; quadratic 0.025). The ability macrophages adhere glass surfaces impaired 0.003). This experiment demonstrates that is cytotoxic vitro.

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