作者: F. Forsberg , J.B. Liu , H.J. Chiou , N.M. Rawool , L. Parker
DOI: 10.1016/S0041-624X(99)00149-3
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摘要: Wideband harmonic imaging (with phase inversion for improved tissue suppression) was compared to fundamental in vivo Four woodchucks with naturally occurring liver tumors were injected Imagent® (Alliance Pharmaceutical Corp., San Diego, CA) Randomized combinations of dose (0.05, 0.2 and 0.4 ml/kg) acoustic output power (AO; 5, 25 63% or MI ≤ 0.9) imaged gray scale using a Sonoline Elegra scanner (Siemens Medical Systems, Issaquah, WA). Tumor vascularity, conspicuity contrast enhancement rated by three independent observers. Imagent produced marked tumor depiction neovascularity at all dosages AO settings both modes. vascularity correlated mode, (P<0.002). Fundamental more (P<0.05), but best appreciated mode (P<0.05). Under the conditions studied here, approach wideband ml/kg an 25%.