Kawasaki Disease: The Debate Continues Till Date

摘要: Tomisaku Kawasaki, a pediatrician saw 4 years old child in 1961 with features of an unknown disease later known as Kawasaki (KD) his honor. He presented findings clinical conference at the Red Cross Hospital Hiroo, Tokyo. A year he came across yet another similar presentation. In following happened to see about 50 more such patients. published 1967 local medical journal Japanese language [1]. The English version was only 1974 [2]. Despite having been reported from almost all parts world ever since 1970s and extensive advancement field, debate on etiology, presentation, epidemiology treatment KD continues till date. is acute febrile illness multi organ vasculitis primarily affecting infants young children under 5 age. It also Mucocutaneous Lymph Node Syndrome (MLNS), infantile vasculitis, syndrome immune vasculitis. Usually small medium sized blood vessels are affected KD. male one half times than female ones. sometimes affects over age rarely encountered adults. Most patients pacific islanders origin often developed including USA particular. has now increasingly developing countries [3-8]. may have some seasonal variations. Genetic constitution be responsible for increased susceptibility Clinical epidemiological suggest that caused by infectious agent. Various agents like rug shampoo, bacteria, viruses, parasites, fungi their super antigens incriminated pathogenesis disease. Recently number reports associate streptococci [9-12]. recent report concludes our knowledge agent (s) involved genetic characteristics susceptible remain partial [13].