Hydroxamate substituted azaindoline-cyanine dyes and bioconjugates of the same

作者: Timothy Dubrovsky , Xing Han , Mirion Schultz , Zhenjun Diwu , Haitao Guo

DOI:

关键词:

摘要: Hydroxamate substituted azaindoline cyanine dyes, conjugates thereof and methods of using the same are provided. The subject dyes include an ring having a hydroxamate substituent. may further reactive group moieties (RGM) and/or water soluble group. Also provided dyes. tandem including fluorescent protein capable energy transfer to dye. Methods detecting analyte in sample by contacting with detection reagent agent be dye-conjugate that specifically binds analyte, or dye which analyte. compositions, e.g., kits, etc., incorporating such facilitate use methods.

参考文章(25)
Fabrice Malergue, Lori A. Charie, Ravinder K. Gupta, Joseph Wolfers, Meryl A. Forman, Francisco Estevez-Labori, Emmanuel Gautherot, Multicolor flow cytometry compositions containing unconjugated phycobiliproteins ,(2009)
Hiroko Inomata, Junji Nishigaki, Masayoshi Kojima, Kazuya Takeuchi, Kouki Nakamura, Fluorescent nucleotides and labeling methods using the same ,(2002)
Xinshe Xu, Lael Cheung, Daniel R. Draney, Cyanine dyes and their conjugates ,(2011)
Ching-Ying Cheung, Wai-Yee Leung, Fei Mao, Hye Eun Hoover, Fluorescent dyes, fluorescent dye kits, and methods of preparing labeled molecules ,(2012)
Raghavan Rajagopalan, Samuel Achilefu, Richard Bradley Dorshow, Joseph Edward Bugaj, Cyanine and indocyanine dye bioconjugates for biomedical applications ,(2000)
Richard B. Dorshow, Joseph E. Bugaj, Raghavan Rajagopalan, Samuel Achilefu, Pathological tissue detection and treatment employing targeted benzoindole optical agents ,(2002)
Thomas Joseph Erickson, Mark Norman Bobrow, Compounds and method for synthesizing sulfoindocyanine dyes ,(1997)
Qinglin Meng, Timothy Dubrovsky, Barnaby Abrams, Zhenjun Diwu, Haitao Guo, Jinfang Liao, Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates ,(2011)
Gary Frenzel, Gregory Gorski, Rajendra Singh, Bridged fluorescent dyes, their preparation and their use in assays ,(2000)