Studies on skin surface barrier functions. Transepidermal water loss and skin surface lipids during childhood.

摘要: Since there are few reports dealing with the barrier efficiency of normal skin during childhood, in vivo experiments were carried out on 40 healthy Japanese children both sexes aged between 3 to 12 years. Two important parameters for properties : transepidermal water loss (TWL) value and surface lipid value, measured by original methods devised course our studies. Statistical analysis was employed understand interrelations those two parameters. The results revealed following characteristic child surface. 1) Inverse correlations found TWL values total forearm skin. Analogous also observed cholesterol values. However, no squalene 2) amount significantly higher than squalene. 3) No statistical significance respect age, sex or weight TWL, lipid, this study. 4) measurements suggested that stratum corneum is nearly same as adult previously reported. 5) It confirmed lipids smaller slightly adults.