Multicenter study on the effect of nonsteroidal anti-inflammatory drugs on postoperative pain after endoscopic sinus and nasal surgery.

摘要: BACKGROUND The taboo of avoiding nonsteroidal anti-inflammatory drugs (NSAIDs) after functional endoscopic sinus surgery (FESS) has been waning. impetus to reduce opioid prescriptions in view the epidemic led authors change their practices include NSAIDs surgery. This study's aim was analyze differences between patients before and we began recommending FESS. METHODS A prospective cohort study performed on undergoing FESS or other nasal surgeries at 3 institutions, by 5 rhinologists 1 facial plastic surgeon. Before introducing NSAIDs, all were given a prescription for hydrocodone-acetaminophen 5/325 mg also recommended preferentially use acetaminophen 325 mg. After addition ibuprofen 200 preferentially, using narcotic as rescue medication. Patients kept pain diary medication log, gave visual analog scale (VAS) score overall pain. Demographics, surgical variables, comorbidities analyzed. RESULTS One hundred sixty-six total recruited had data that could be analyzed (65 without 101 with NSAIDs). Overall, mean VAS 3.12 ± 1.95 non-NSAID group 2.33 2.30 NSAID (p value = 0.006). day highest first postoperative day. number pills taken 6.94 6.85 vs 3.77 4.56 0.018). Age gender found only consistently significant patient variables affect There no bleeding complications. CONCLUSION introduced into practicing No complications seen. Both usage reduced significantly.