Evaluation of pooled screening for anti-HCV in two blood services set-ups.

摘要: Summary Objective Screening blood donations for anti-HCV is only partially performed in many developing countries due to the relatively high costs of testing. The screening expenditures can be reduced by testing pools. This study evaluates accuracy and feasibility pooled procedure banks Israel Palestinian Authority. Methods sensitivity specificity tests on pool sizes 6–24 samples were compared singleton immunoassay All negative those positive obtained from routine work Magen David Adom Blood Services Shifa Hospital bank Authority. experiments run parallel with different technologies. Results  pooled-testing was 94–97% verified samples. In Hospital, estimated as 96–97% non-verified Cost-analysis showed benefits up $2 per donation screened Hospital. Conclusions  We recommend using manually created pools 6 when anti-HCV, but at cost 3% loss sensitivity. Pooling considered, which do not perform screening, their limited economic resources. Objectifs  Le criblage des dons de sang pour l'anti-VHC est seulement partiellement execute dans beaucoup pays en voie developpement a cause couts relativement eleves du test. Les depenses le peuvent etre reduites testant les par pools. Cette etude evalue la precision et praticabilite procede poolage l'anti- VHC banques l'autorite palestinienne. Methodes  La sensibilite specificite l'immunoessai realise sur tailles 24 echantillons ont ete comparees celles singletons. Tous negatifs positifs obtenus services banque l'hopital palestinienne. experiences menees parallele avec differentes technologies. Resultats  test etait verifies. Dans Shifa, estimee non L'analyse revele avantages allant jusqu’a 2 dollars US don examine Shifa. Conclusions  Nous recommandons l'utilisation manuel VHC, toutefois une perte sensibilite. peut considere n'effectuant pas ressources economiques limitees. Objetivos  El tamizaje sangre donantes para anti-VHC se realiza solo forma parcial muchos paises vias desarrollo, debido al costo relativamente alto las pruebas. Los gastos pueden reducirse si realizan pruebas agrupando muestras (pooling). En este estudio evalua y viabilidad realizar un agrupado bancos Palestina. Metodos  sensibilidad especificidad realizadas grupos fueron comparadas con unicas mediante inmunoensayo. Todas negativas, aquellas positivas anti-VHC, obtuvieron del trabajo rutina los Adon el Palestina. experimentos realizados paralelo utilizando diferentes tecnologias. Resultados  fue previamente verificadas. estimo no analisis costes mostro beneficios hasta por donacion tamizada Hospital. Conclusiones  Recomendamos utilizar agrupacion muestras, manual total subsiguiente perdida sensibilidad. agrupar puede ser una opcion que limitacion recursos economicos.