Changes in expression of hepatic genes involved in lipid metabolism during prehibernation period in captive adult female Japanese black bears (Ursus thibetanus japonicus)
作者： Michito Shimozuru , Kamine Akari , Toshio Tsubota
DOI: 10.1139/Z2012-062
关键词:
摘要: Body fat accumulation in the prehibernation period is crucial for survival and reproduction during hibernation bears. Bear body mass increases rapidly their autumnal hyperphagia phase, which attributed not only to an increase food availability, but also physiological changes lipid metabolism. To test this hypothesis, we investigated blood biochemical values mRNA expression levels of hepatic genes involved metabolism active (June, August, October, November) Japanese black bears (Ursus thibetanus japonicus Schlegel, 1857), were fed a constant ration throughout period. Blood analysis revealed that plasma triglyceride concentrations decreased October November, implying peripheral uptake was accelerated autumn. The liver sampled by needle biopsy. Real-time polymerase chain reaction (PCR) expressions enzymes glycolysis (glucokinase), as well as...
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