Chronic Deafferentation of Human Spinal Cord Neurons

摘要: T HE study of focal cortical epilepsy has led us to the belief that epileptic neurons are partially deafferentY The validity this hypothesis been demonstrated in cat spinal cord where rhizotomy or hemi-cordotomy result neuronal firing patterns similar those seen an focus. 1 Other work our laboratories shown certain epileptogenic agents, when injected into cat, can produce unusual sensory states suggestive pain and typical epilepsy? It is many central occur after nerve injury may be due chronic deafferentation subsequent hyperactivity at segmental level. This report describes a paraplegic patient whose activity was sampled.