Measurement uncertainty for the determination of amphetamines in urine by liquid-phase microextraction and gas chromatography-mass spectrometry
作者： Mauricio Yonamine ,
DOI: 10.1016/J.FORSCIINT.2016.01.012
关键词:
摘要: A gas chromatography-mass spectrometry method for the determination of amphetamines in urine samples by means liquid-phase microextraction was validated, including calculation measurement uncertainty. After extraction three-phase mode, acceptor phase withdrawn from fiber and residue derivatized with trifluoroacetic anhydride. The showed to be very simple, rapid it required a significantly low amount organic solvent extraction. limits detection were 10 20μg/L amphetamine methamphetamine, respectively. calibration curves linear over specified range (20μg/L 1400μg/L; r(2)>0.99). both precise accurate relative combined uncertainty 2% calculated. In order importance, factors which more determinant were: analyte concentration, sample volume, trueness precision.
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Frank T. Peters, Olaf H. Drummer, Frank Musshoff, Validation of new methods. Forensic Science International. ,vol. 165, pp. 216- 224 ,(2007) , 10.1016/J.FORSCIINT.2006.05.021
Stig Pedersen-Bjergaard, Knut Einar Rasmussen, Liquid-phase microextraction with porous hollow fibers, a miniaturized and highly flexible format for liquid–liquid extraction Journal of Chromatography A. ,vol. 1184, pp. 132- 142 ,(2008) , 10.1016/J.CHROMA.2007.08.088
Abdulmumin A. Nuhu, Chanbasha Basheer, Bahruddin Saad, Liquid-phase and dispersive liquid–liquid microextraction techniques with derivatization: Recent applications in bioanalysis Journal of Chromatography B. ,vol. 879, pp. 1180- 1188 ,(2011) , 10.1016/J.JCHROMB.2011.02.009
Zengping Huang, Shaoyu Zhang, Confirmation of amphetamine, methamphetamine, MDA and MDMA in urine samples using disk solid-phase extraction and gas chromatography-mass spectrometry after immunoassay screening. Journal of Chromatography B. ,vol. 792, pp. 241- 247 ,(2003) , 10.1016/S1570-0232(03)00269-1
Jing-Shan Chiang, Shang-Da Huang, Simultaneous derivatization and extraction of amphetamine and methylenedioxyamphetamine in urine with headspace liquid-phase microextraction followed by gas chromatography-mass spectrometry. Journal of Chromatography A. ,vol. 1185, pp. 19- 22 ,(2008) , 10.1016/J.CHROMA.2008.01.038
Mitsuhiro Wada, Yuki Sugimoto, Brian L. Crabtree, Cynthia Evans, John H. Montgomery, Rie Ikeda, Naotaka Kuroda, Kenichiro Nakashima, Simultaneous determination of amphetamine-type stimulants in abusers’ hair: clinical usefulness of hair analysis in prehospitalization for abusers Forensic Toxicology. ,vol. 31, pp. 2- 8 ,(2013) , 10.1007/S11419-012-0153-6
Takeshi Saito, Hiroyasu Mase, Sanae Takeichi, Sadaki Inokuchi, Rapid simultaneous determination of ephedrines, amphetamines, cocaine, cocaine metabolites, and opiates in human urine by GC-MS. Journal of Pharmaceutical and Biomedical Analysis. ,vol. 43, pp. 358- 363 ,(2007) , 10.1016/J.JPBA.2006.06.031
Lorena do Nascimento Pantaleão, Beatriz Aparecida Passos Bismara Paranhos, Mauricio Yonamine, Hollow-fiber liquid-phase microextraction of amphetamine-type stimulants in human hair samples. Journal of Chromatography A. ,vol. 1254, pp. 1- 7 ,(2012) , 10.1016/J.CHROMA.2012.07.014
Jun Xiong, Jie Chen, Man He, Bin Hu, Simultaneous quantification of amphetamines, caffeine and ketamine in urine by hollow fiber liquid phase microextraction combined with gas chromatography-flame ionization detector. Talanta. ,vol. 82, pp. 969- 975 ,(2010) , 10.1016/J.TALANTA.2010.06.001
Malcolm Burns, Current practice in the assessment and control of measurement uncertainty in bio-analytical chemistry Trends in Analytical Chemistry. ,vol. 23, pp. 393- 398 ,(2004) , 10.1016/S0165-9936(04)00523-0