Cerebral Microbleeds: Histopathology of cerebral microbleeds

摘要: This chapter describes the development of knowledge concerning microaneurysmal and small hemorrhagic lesions in relation to intracerebral hemorrhage (ICH) vessel diseases, which may be relevant understanding origin radiologically defined cerebral microbleeds (CMBs). The hypothesis that has arisen from work Jean-Martin Charcot Charles-Joseph Bouchard is pathological changes (degenerative or inflammatory, often associated with arterial hypertension) caliber arterioles (up approximately 300 µm) cause weakening wall microaneurysm formation, subsequently rupture ICH. Cerebral are particularly common ICH suggesting they provide clues underlying could potentially shed light on role microaneurysms. amyloid angiopathy now recognized as a disorder elderly populations characterized by deposition cortical leptomeningeal vessels.