Réévaluation des risques respectifs d'anaphylaxie et d'histaminolibération avec les substances anesthésiologiques

摘要: A search of the French and English language literature last 20 years (1964-1984) yielded 975 cases immediate anaphylactoid reactions due to anaesthetic drugs given parenterally. The accident mechanism was confirmed in only half patients, nearly always at a later date. immunoallergological tests most often used diagnostic process were skin Prausnitz-Kustner tests. Although all could be responsible for an anaphylactic reaction, greatest number muscle relaxants (51%) hypnotic (42.3%). signs described cutaneous, cardiovascular, respiratory occasionally gastro-intestinal. Whilst cutaneous signs, gave cardiovascular signs. past history drug allergy found 37% cases, atopy 38%; virtually patients had already one or more anaesthetics.