The ups and downs of DNA repair biomarkers for PARP inhibitor therapies
作者： XiaoZhe Wang , David T Weaver
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摘要: PARP inhibitors are emerging as a valuable new drug class in the treatment of cancer. Recent discoveries make compelling case for complexity DNA repair biomarker evaluation and underscore need to examine at multiple biomarkers relational manner. This review updates current trends strategies use describes impact many on inhibitor benefit cancer clinic.
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