Clinical Update: Cardiovascular Disease in Diabetes Mellitus: Atherosclerotic Cardiovascular Disease and Heart Failure in Type 2 Diabetes Mellitus – Mechanisms, Management, and Clinical Considerations
作者： Cecilia C. Low Wang , Connie N. Hess , William R. Hiatt , Allison B. Goldfine
DOI: 10.1161/CIRCULATIONAHA.116.022194
关键词:
摘要: Cardiovascular disease remains the principal cause of death and disability among patients with diabetes mellitus. Diabetes mellitus exacerbates mechanisms underlying atherosclerosis heart failure. Unfortunately, these are not adequately modulated by therapeutic strategies focusing solely on optimal glycemic control currently available drugs or approaches. In setting multifactorial risk reduction statins other lipid-lowering agents, antihypertensive therapies, antihyperglycemic treatment strategies, cardiovascular complication rates falling, yet remain higher for than those without. This review considers mechanisms, history, controversies, new pharmacological recent evidence current guidelines management in patient to support evidence-based care outside acute setting.
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