Ecological significance of mitochondrial toxicants.

摘要: Abstract Mitochondrial dysfunction with exposure to anthropogenic contaminants is a critical concern in biomedical and ecological health. Importantly, understanding the role of mitotoxicants modulating organismal fitness survival, particularly context species’ resilience shifts abiotic factors climate change, emerging as key consideration. To date, only few studies have focused on effects responses additional stressors ( e.g. , temperature, levels oxygen, salinity); however, these serve demonstrate that chemical could alter stress responses. Here theoretical framework presented integrate mitochondrial into response stressors, highlighting importance sustaining capacity conserve or regenerate healthy population mitochondria, i.e. maintaining plasticity, multi-stressor environment. The complexity mitochondria-associated processes impact fate transport chemicals change are also considered. Considering crucial mitochondria environments their vulnerability physical this review proposes use function physiological marker species environmental change. Finally, impacts health wildlife important own right, but potential studies, especially DNA analyses, inform long-term human discussed.