Predictors of non-healing in patients with critical limb ischemia and tissue loss following successful endovascular therapy.

摘要: Objectives To evaluate the predictors of non-healing in patients with critical limb ischemia (CLI) after successful endovascular therapy (EVT). Background Occasionally, wound healing CLI and tissue loss cannot be achieved even EVT. Patient's co-morbidities, vascular anatomy, features, interventional strategies/outcomes are associated probability healing. Methods Between April 2007 October 2012, 182 (220 limbs) were treated EVT our institute. Of these, 164 individual wounds (130 patients, 149 out 243 successfully treated. Successful was defined as revascularization by achieving visible blood flow to wounds, evaluated digital subtraction angiography performed just A Cox proportional hazards model used analyze healing. Results The mean follow-up period 23 ± 18 months. The rates 40.2%, 57.3%, 62.2%, 70.7% at 3, 6, 9, 12 months, respectively. Multivariate analysis revealed that insulin use [hazard ratio (HR), 0.541; 95% confidence interval (CI), 0.329–0.890; P = 0.016], dependence on hemodialysis [HR, 0.429; CI, 0.272–0.678; P < 0.001], major 0.460; 0.294–0.720; P = 0.001] independent EVT. Conclusions Insulin use, hemodialysis, © 2014 Wiley Periodicals, Inc.