Regulation by the yeast mating-type locus of STE12, a gene required for cell-type-specific expression.

作者: S Fields , I Herskowitz

DOI: 10.1128/MCB.7.10.3818

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摘要: The STE12 gene of the yeast Saccharomyces cerevisiae is necessary for RNA synthesis from two sets cell-type-specific genes. We isolated a recombinant plasmid that carries by complementation mating defect ste12 cells. DNA cloned was used to disrupt chromosomal and identify transcript. show transcript level repressed 5- 10-fold in a/alpha product thus acts promote diploidy activating expression genes mating, then its products unique diploid cell type.

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