C-MYB AND CREB FUNCTION IN ADULT NEUROGENESIS

摘要: The molecular pathways regulating post-natal neurogenesis are poorly understood. c-Myb is recognised as maintaining haemopoietic and colonic cells in an undifferentiated state, while CREB known to be important for neuronal cell survival function. These properties a neural progenitor population adult brain. We review the literature that suggests co-regulate number of factors involved neurogenesis. Emerging data discussed, which shows c- Myb required normal postnatal brain development mouse, we consider how these mice will used identify co-regulated by CREB, specifically