The effect of a probiotic on faecal and liver lipid classes in rats.

作者: Michihiro Fukushima , Masuo Nakano

DOI: 10.1079/BJN19950074

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摘要: The effect of a probiotic composed Bacillus, Lactobacillus, Streptococcus, Saccharomyces and Candida species (each at 107–8 colony-forming units (cfu)/g rice bran), given level 150 g/kg diet for 6 weeks, on lipid metabolism was examined in the faeces, serum liver male rats. Liver weight decreased 35% rats fed high-fat, high-cholesterol containing probiotic. Total cholesterol concentration significantly lower group than control throughout experimental period diet, HDL-cholesterol higher (P < 0·05) which week basal diet. VLDL + IDL LDL concentrations groups were reduced compared with those corresponding groups. had hepatic did 0·05). Hydroxymethylglutaryl coenzyme A reductase (NADPH) (EC. 1.1.1.34) activity neutral acidic steroid faeces Escherichia coli Bifidobacterium Eubacterium increased faecal microflora dietary Lactobacillus that present study shows promotes microflora, reduces levels

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