摘要: Human tumours grown in immune-deficient mice are available for studies experimental pathology and therapeutics. In addition to growth-delay experiments clonogenic assays can sometimes be performed. Xenografts often retain some characteristics of the source tumour but amount precise information on maintenance therapeutic sensitivity is small. Principal drawbacks include difficulty matching with human doses dose drugs given host mouse, probable existence a substantial reaction against grafts. benefits may that involve intercomparison regard response.
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