Silinane compounds as cysteine protease inhibitors
作者： Michael Graupe , John O. Link
DOI:
关键词:
摘要: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S therefore useful treating diseases mediated by these proteases. also pharmaceutical compositions comprising processes for preparing them. the use combination with a therapy causes deleterious immune response patients receiving therapy.
lens.org 参考文章(5)
Hidde L. Ploegh, Richard J. Riese, Harold A. Chapman, Matthew S. Bogyo, Paula R. Bryant, Suppression of immune response via inhibition of cathepsin S ,(1997)
Michael Graupe, John O. Link, Peptidic compounds as cysteine protease inhibitors ,(2003)
Craig J. Mossman, Sheila M. Zipfel, John O. Link, Soon H. Woo, Haloalkyl containing compounds as cysteine protease inhibitors ,(2004)
Shankar Venkatraman, Clifford M. Bryant, Dan-Xiong Wang, James T. Palmer, Robert M. Rydzewski, Zong-Qiang Tian, Eduardo L. Setti, Novel compounds and compositions as protease inhibitors ,(2000)
Valeri Martichonok, Sheila Zipfel, Oliver L. Saunders, John O. Link, John W. Patterson, Arnold J. Martelli, Amine derivatives as protease inhibitors ,(2000)