Peptidic compounds as cysteine protease inhibitors
作者： Michael Graupe , John O. Link
DOI:
关键词:
摘要: The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S therefore useful treating diseases mediated by these proteases. pharmaceutical compositions comprising processes for preparing them.
lens.org 参考文章(18)
Irwin D. Kuntz, Diana C. Roe, Ellen K. Kick, Jonathan A. Ellman, Christina E. Lee, A. Geoffrey Skillman, Guangcheng Liu, Nanomolar, non-peptide inhibitors of cathepsin d ,(1998)
James Palmer, Sulfonamide compounds as protease inhibitors ,(2002)
Sheila Zipfel, John O. Link, John W. Patterson, Michael Graupe, Compounds and pharmaceutical compositions as cathepsin s inhibitors ,(2000)
Hidde L. Ploegh, Richard J. Riese, Harold A. Chapman, Matthew S. Bogyo, Paula R. Bryant, Suppression of immune response via inhibition of cathepsin S ,(1997)
Sukanthini Thurairatnam, Michael Graupe, James T. Palmer, David J. Aldous, Novel compounds and compositions as cathepsin inhibitors ,(2002)
Kathleen Okamoto, Dieter Brömme, Cathepsin o2 protease ,(1995)
Benito Munoz, Elisabeth Albrecht, Ian Alexander Mcdonald, Peptide, peptide analog and amino acid analog protease inhibitors ,(1995)
T. YASUMA, S. OI, N. CHOH, T. NOMURA, N. FURUYAMA, A. NISHIMURA, Y. FUJISAWA, T. SOHDA, Synthesis of Peptide Aldehyde Derivatives as Selective Inhibitors of Human Cathepsin L and Their Inhibitory Effect on Bone Resorption. ChemInform. ,vol. 30, ,(1999) , 10.1002/CHIN.199912205
Denice Mary Spero, Younes Bekkali, Yancey D. Ward, David S. Thomson, Sanxing Sun, Erick R. R. Young, Weimin Liu, Usha R. Patel, Eugene R. Hickey, Compounds useful as reversible inhibitors of cysteine proteases ,(2002)
Mary P. Zimmerman, Robert E. Smith, Cysteine protease inhibitors containing heterocyclic leaving groups ,(1994)