Pathway for Hydrolysis of Plasmalogens in Brain
作者： Lloyd A. Horrocks , Sheung Chun Fu
DOI: 10.1007/978-1-4615-9071-2_37
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摘要: The ethanolamine plasmalogens in brain have a substantial rate of turnover (Horrocks et al., 1976). Hydrolytic degradation the plasmalogen molecule could begin at any position. Evidence for phospholipase C (EC 3.1.4.3) has been reported (Williams 1973; Abra and Quinn, 1975). Diglycerides can also be released by reversal phosphotransferase 2.7.8.1) presence CMP. Brain contains A2 but its activity is much less with than diacyl phosphoglycerides (Woelk Porcellati, 1973). Plasmalogenase 3.3.2.–) cleaves alk-1-enyl group to release long-chain aldehyde. None these enzymes, except plasmalogenase, seem possess necessary account plasmalogens.
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