Protein–protein interactions and genetic diseases: The interactome
作者： Kasper Lage
DOI: 10.1016/J.BBADIS.2014.05.028
关键词:
摘要: Protein-protein interactions mediate essentially all biological processes. Despite the quality of these data being widely questioned a decade ago, reproducibility large-scale protein interaction is now much improved and there little question that latest screens are high quality. Moreover, common standards coordinated curation practices between databases collect have made valuable available to wide group researchers. Here, I will review how protein-protein measured, collected controlled. discuss architecture molecular networks has informed disease biology, computationally integrated with newest genomic technologies, in particular genome-wide association studies exome-sequencing projects, improve our understanding processes perturbed by genetics human diseases. This article part Special Issue entitled: From Genome Function.
core.ac.uk
elsevier.com
sci-hub.se 参考文章(124)
T. Ideker, A. Valencia, Bioinformatics in the human interactome project Bioinformatics. ,vol. 22, pp. 2973- 2974 ,(2006) , 10.1093/BIOINFORMATICS/BTL579
K. Lage, S. C. Greenway, J. A. Rosenfeld, H. Wakimoto, J. M. Gorham, A. V. Segre, A. E. Roberts, L. B. Smoot, W. T. Pu, A. C. Pereira, S. M. Mesquita, N. Tommerup, S. Brunak, B. C. Ballif, L. G. Shaffer, P. K. Donahoe, M. J. Daly, J. G. Seidman, C. E. Seidman, L. A. Larsen, Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 109, pp. 14035- 14040 ,(2012) , 10.1073/PNAS.1210730109
, M. Dreze, A.-R. Carvunis, B. Charloteaux, M. Galli, S. J. Pevzner, M. Tasan, Y.-Y. Ahn, P. Balumuri, A.-L. Barabasi, V. Bautista, P. Braun, D. Byrdsong, H. Chen, J. D. Chesnut, M. E. Cusick, J. L. Dangl, C. de los Reyes, A. Dricot, M. Duarte, J. R. Ecker, C. Fan, L. Gai, F. Gebreab, G. Ghoshal, P. Gilles, B. J. Gutierrez, T. Hao, D. E. Hill, C. J. Kim, R. C. Kim, C. Lurin, A. MacWilliams, U. Matrubutham, T. Milenkovic, J. Mirchandani, D. Monachello, J. Moore, M. S. Mukhtar, E. Olivares, S. Patnaik, M. M. Poulin, N. Przulj, R. Quan, S. Rabello, G. Ramaswamy, P. Reichert, E. A. Rietman, T. Rolland, V. Romero, F. P. Roth, B. Santhanam, R. J. Schmitz, P. Shinn, W. Spooner, J. Stein, G. M. Swamilingiah, S. Tam, J. Vandenhaute, M. Vidal, S. Waaijers, D. Ware, E. M. Weiner, S. Wu, J. Yazaki, Evidence for Network Evolution in an Arabidopsis Interactome Map Science. ,vol. 333, pp. 601- 607 ,(2011) , 10.1126/SCIENCE.1203877
Chris Cotsapas, Benjamin F. Voight, Elizabeth Rossin, Kasper Lage, Benjamin M. Neale, Chris Wallace, Gonçalo R. Abecasis, Jeffrey C. Barrett, Timothy Behrens, Judy Cho, Philip L. De Jager, James T. Elder, Robert R. Graham, Peter Gregersen, Lars Klareskog, Katherine A. Siminovitch, David A. van Heel, Cisca Wijmenga, Jane Worthington, John A. Todd, David A. Hafler, Stephen S. Rich, Mark J. Daly, , Pervasive Sharing of Genetic Effects in Autoimmune Disease PLoS Genetics. ,vol. 7, pp. e1002254- ,(2011) , 10.1371/JOURNAL.PGEN.1002254
Rod Taylor, Moyez Dharsee, Yuen Ho, Adrian Heilbut, Lynda Moore, Shudong Zhang, Olga Ornatsky, Yury V Bukhman, Martin Ethier, Yinglun Sheng, Julian Vasilescu, Mohamed Abu‐Farha, Jean‐Philippe Lambert, Henry S Duewel, Ian I Stewart, Bonnie Kuehl, Kelly Hogue, Karen Colwill, Katharine Gladwish, Brenda Muskat, Robert Kinach, Sally‐Lin Adams, Michael F Moran, Gregg B Morin, Thodoros Topaloglou, Daniel Figeys, Rob M Ewing, Peter Chu, Fred Elisma, Hongyan Li, Paul Taylor, Shane Climie, Linda McBroom‐Cerajewski, Mark D Robinson, Liam O'Connor, Michael Li, Large‐scale mapping of human protein–protein interactions by mass spectrometry Molecular Systems Biology. ,vol. 3, pp. 89- 89 ,(2007) , 10.1038/MSB4100134
Gregory Hannum, Rohith Srivas, Aude Guénolé, Haico van Attikum, Nevan J. Krogan, Richard M. Karp, Trey Ideker, Genome-Wide Association Data Reveal a Global Map of Genetic Interactions among Protein Complexes PLoS Genetics. ,vol. 5, pp. e1000782- ,(2009) , 10.1371/JOURNAL.PGEN.1000782
A. Subramanian, P. Tamayo, V. K. Mootha, S. Mukherjee, B. L. Ebert, M. A. Gillette, A. Paulovich, S. L. Pomeroy, T. R. Golub, E. S. Lander, J. P. Mesirov, Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles Proceedings of the National Academy of Sciences of the United States of America. ,vol. 102, pp. 15545- 15550 ,(2005) , 10.1073/PNAS.0506580102
Ioannis Xenarios, Lukasz Salwinski, Xiaoqun Joyce Duan, Patrick Higney, Sul-Min Kim, David Eisenberg, DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions Nucleic Acids Research. ,vol. 30, pp. 303- 305 ,(2002) , 10.1093/NAR/30.1.303
Gosia Trynka, Cynthia Sandor, Buhm Han, Han Xu, Barbara E Stranger, X Shirley Liu, Soumya Raychaudhuri, Chromatin marks identify critical cell types for fine mapping complex trait variants Nature Genetics. ,vol. 45, pp. 124- 130 ,(2013) , 10.1038/NG.2504
Yun Niu, David Otasek, Igor Jurisica, Evaluation of linguistic features useful in extraction of interactions from PubMed; Application to annotating known, high-throughput and predicted interactions in I2D Bioinformatics. ,vol. 26, pp. 111- 119 ,(2010) , 10.1093/BIOINFORMATICS/BTP602