Recognition Roles of Mammalian Structural Units and Polyvalency in Lectin–Glycan Interactions

作者: Albert M. Wu , Jia-Haw Liu , Tanuja Singh , Zhangung Yang

DOI: 10.1007/978-1-4419-7877-6_6

关键词:

摘要: Lectins are an important class of proteins or glycoproteins nonimmune origin that specifically selectively bind carbohydrate moieties complex carbohydrates. They play many critical roles in life processes, such as fertilization, embryogenesis, cell migration, organ formation, inflammation, immune defense, and microbial infection [8, 22, 40]. Specificity lectins toward particular structures allows them to be used for characterization unknown identification fractionation glycoconjugates [23]. Moreover, this unique group has provided researchers with powerful tools explore biological processes which involved. Considering the role vivo, we have realize living organisms interact multivalent macromolecules (glycoproteins) clusters oligosaccharide ligands on surface.

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