Structural snapshots along the reaction pathway of ferredoxin–thioredoxin reductase
作者： Shaodong Dai , Rosmarie Friemann , Dominique A. Glauser , Florence Bourquin , Wanda Manieri
DOI: 10.1038/NATURE05937
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摘要: Oxygen-evolving photosynthetic organisms regulate carbon metabolism through a light-dependent redox signalling pathway. Electrons are shuttled from photosystem I by means of ferredoxin (Fdx) to ferredoxin–thioredoxin reductase (FTR), which catalyses the two-electron-reduction of chloroplast thioredoxins (Trxs). These modify target enzyme activities by reduction, regulating carbon flow. FTR is unique in its use of a [4Fe–4S] cluster and a proximal disulphide bridge in the conversion of a light signal into a thiol signal. We …
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