Early versus delayed enteral nutrition support for burn injuries

摘要: Background A burn injury increases the body's metabolic demands, and therefore nutritional requirements. Provision of an adequate supply nutrients is believed to lower incidence abnormalities, thus reducing septic morbidity, improving survival rates, decreasing hospital length stay. Enteral nutrition support best feeding method for patients who are unable achieve oral intake maintain gastrointestinal functioning, however, its timing (i.e. early versus late) needs be established. Objectives To assess effectiveness safety late enteral in adults with injury. Search methods We searched Cochrane Injuries Group's Specialised Register (Dec 2007), CENTRAL (The Library, issue 4, MEDLINE (1966 December, EMBASE (1980 December 2007) CINAHL (1982 May, 2006). Selection criteria We included all randomised controlled trials comparing (within 24 hours injury) delayed (greater than hours). Data collection analysis Two authors used standardised forms independently extract data. Each trial was assessed internal validity differences resolved by discussion. Main results A total three were eligible inclusion this review. Results studies indicate that evidence about benefit on clinical outcomes such as stay mortality, remains inconclusive. Similarly, question whether influenced or decreased rate documented part our studies, uncertain. Authors' conclusions This systematic review has not found sufficient refute injury. The showed some promising results would suggest may blunt hypermetabolic response thermal injury, but insufficient provide clear guidelines practice. Further research incorporating larger sample sizes rigorous methodology utilises valid reliable outcome measures, essential.