Treatment of 125 sinonasal tumors: prognostic factors, outcome, and follow-up.

作者: José L. Blanch , Aída M. Ruiz , Llúcia Alos , Josep Traserra-Coderch , Manuel Bernal-Sprekelsen

DOI: 10.1016/J.OTOHNS.2004.08.001

关键词:

摘要: We reviewed our experience with sinonasal cancer patients to assess the prognostic factors. Between 1974 and 1995, we enrolled 125 (58 + 16 years [mean age SD]; 94 males 31 females). Tumor stage distribution was: T1, 64 patients; T2, 36 T3, 25 patients. Surgery as a primary treatment was selected for 106 (55 cases of surgery alone, 40 plus radiotherapy, 11 chemotherapy with/without radiotherapy). The 1-, 5-, 10-year overall survival 75.0%, 37.2%, 24.7%, respectively. parameters statistical significance were nodal stage, locoregional failure, tumor stage. Histological type site had no value. There significant differences between alone radiotherapy. Sinonasal tumors have poor survival, despite early diagnosis, radical surgical resection, strict follow-up. Radiotherapy seems not be clearly necessary in T1.

参考文章(14)
S. W. Hone, T. G. O’Leary, A. Maguire, H. Burns, C. I. Timon, Malignant sinonasal tumours: the Dublin Eye and Ear Hospital experience. Irish Journal of Medical Science. ,vol. 164, pp. 139- 141 ,(1995) , 10.1007/BF02973281
Shankar P. G. Giri, Eashwer K. Reddy, Linda S. Getner, Leela Krishnan, Stephen R. Smalley, Richard G. Evans, Management of advanced squamous cell carcinomas of the maxillary sinus Cancer. ,vol. 69, pp. 657- 661 ,(1992) , 10.1002/1097-0142(19920201)69:3<657::AID-CNCR2820690310>3.0.CO;2-7
Jeffrey D. Spiro, Kee Chee Soo, Ronald H. Spiro, Nonsquamous cell malignant neoplasms of the nasal cavities and paranasal sinuses Head and Neck-journal for The Sciences and Specialties of The Head and Neck. ,vol. 17, pp. 114- 118 ,(1995) , 10.1002/HED.2880170207
Guo-Liang Jiang, William H Morrison, Adam S Garden, Fady Geara, David Callender, Helmuth Goepfert, K.Kian Ang, Ethmoid sinus carcinomas: natural history and treatment results Radiotherapy and Oncology. ,vol. 49, pp. 21- 27 ,(1998) , 10.1016/S0167-8140(98)00075-9
Arnold C. Paulino, James E. Marks, Preston Bricker, Edward Melian, Sarada P. Reddy, Bahman Emami, Results of treatment of patients with maxillary sinus carcinoma Cancer. ,vol. 83, pp. 457- 465 ,(1998) , 10.1002/(SICI)1097-0142(19980801)83:3<457::AID-CNCR14>3.0.CO;2-V
Francesco Carinci, Antonio Farina, Ernesto Padula, Carlo Calearo, Primary Malignancies of the Nasal Fossa and Paranasal Sinuses: Comparison Between UICC Classification and a New Staging System Journal of Craniofacial Surgery. ,vol. 8, pp. 405- 412 ,(1997) , 10.1097/00001665-199708050-00014
James T. Parsons, William M. Mendenhall, Anthony A. Mancuso, Nicholas J. Cassisi, Rodney R. Million, Malignant tumors of the nasal cavity and ethmoid and sphenoid sinuses. International Journal of Radiation Oncology Biology Physics. ,vol. 14, pp. 11- 22 ,(1988) , 10.1016/0360-3016(88)90044-2
Ralph P. Tufano, Nahush A. Mokadam, Kathleen T. Montone, Gregory S. Weinstein, Ara A. Chalian, Patricia F. Wolf, Randal S. Weber, Malignant tumors of the nose and paranasal sinuses: hospital of the University of Pennsylvania experience 1990-1997. American Journal of Rhinology. ,vol. 13, pp. 117- 123 ,(1999) , 10.2500/105065899782106698
Koh-Ichi Sakata, Yukimasa Aoki, Katsuyuki Karasawa, Keiichi Nakagawa, Kenji Hasezawa, Nobuharu Muta, Atsuro Terahara, Yuzo Onogi, Yasuhito Sasaki, Atsuo Akanuma, Analysis of the results of combined therapy for maxillary carcinoma. Cancer. ,vol. 71, pp. 2715- 2722 ,(1993) , 10.1002/1097-0142(19930501)71:9<2715::AID-CNCR2820710905>3.0.CO;2-0
Grethe Harbo, Cai Grau, Troels Bundgaard, Marie Overgaard, Ole Elbrønd, Helmer Søgaard, Jens Overgaard, Cancer of the Nasal Cavity and Paranasal Sinuses: A Clinico-pathological Study of 277 Patients Acta Oncologica. ,vol. 36, pp. 45- 50 ,(1997) , 10.3109/02841869709100731