Frequency of CYP2C9 genotypes among Omani patients receiving warfarin and its correlation with warfarin dose.

作者: Musbah O. Tanira , Mohammed K. Al-Mukhaini , Ali T. Al-Hinai , Khalid A. Al Balushi , Ikhlas S. Ahmed

DOI: 10.1159/000096279

关键词:

摘要: Objectives: This study was conducted to determine the frequency of CYP2C9 alleles in Omani patients receiving warfarin and correlate genotyping data with dosage. The Oma

参考文章(32)
Joyce A. Goldstein, CYP2C9 polymorphisms and CYP2C9*2 genotyping primers British Journal of Clinical Pharmacology. ,vol. 53, pp. 409- 410 ,(2002) , 10.1046/J.1365-2125.2002.01572_7.X
Maria Gabriella Scordo, Eleni Aklillu, Umit Yasar, Marja-Liisa Dahl, Edoardo Spina, Magnus Ingelman-Sundberg, Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population. British Journal of Clinical Pharmacology. ,vol. 52, pp. 447- 450 ,(2001) , 10.1046/J.0306-5251.2001.01460.X
Young-Ran Yoon, Ji-Hong Shon, Moon-Kyung Kim, Young-Chai Lim, Hye-Rang Lee, Ji-Young Park, In-June Cha, Jae-Gook Shin, Frequency of cytochrome P450 2C9 mutant alleles in a Korean population. British Journal of Clinical Pharmacology. ,vol. 51, pp. 277- 280 ,(2001) , 10.1046/J.1365-2125.2001.00340.X
Michael J. Stubbins, Lorna W. Harries, Gillian Smith, Michael H. Tarbit, C Roland Wolf, Genetic analysis of the human cytochrome P450 CYP2C9 locus. Pharmacogenetics. ,vol. 6, pp. 429- 439 ,(1996) , 10.1097/00008571-199610000-00007
Hong-Guang Xie, Harish C Prasad, Richard B Kim, C.Michael Stein, CYP2C9 allelic variants: ethnic distribution and functional significance Advanced Drug Delivery Reviews. ,vol. 54, pp. 1257- 1270 ,(2002) , 10.1016/S0169-409X(02)00076-5
Dan M. Roden, Alfred L. George Jr, The genetic basis of variability in drug responses Nature Reviews Drug Discovery. ,vol. 1, pp. 37- 44 ,(2002) , 10.1038/NRD705
Patrizia Ferrari, Pharmacogenomics: a new approach to individual therapy of hypertension? Current Opinion in Nephrology and Hypertension. ,vol. 7, pp. 217- 222 ,(1998) , 10.1097/00041552-199803000-00012
Kenji Takanashi, Hitoshi Tainaka, Kaoru Kobayashi, Toshio Yasumori, Masakiyo Hosakawa, Kan Chiba, CYP2C9 Ile359 and Leu359 variants: enzyme kinetic study with seven substrates. Pharmacogenetics. ,vol. 10, pp. 95- 104 ,(2000) , 10.1097/00008571-200003000-00001
Charles Eby, Paul Milligan, Gerald Banet, Jill Duncan, Howard McLeod, Brian Gage, Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin. Thrombosis and Haemostasis. ,vol. 91, pp. 87- 94 ,(2003) , 10.1160/TH03-06-0379