Molecular profiling of disease and therapeutic response using phospho-specific antibodies
作者： Katherine Crosby , Bradley Smith
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摘要: The present invention provides methods for identifying the most relevant signal transduction pathway biomarkers of disease progression, outcome, or therapeutic responsiveness, using phospho-specific antibodies in cellular assays to identify proteins whose activity is correlated outcome (e.g. responsiveness). also a method utilizing biomarker(s) predict patient response composition having efficacy against involving altered by employing one more detect activation status such assays. Kits carrying out are provided.
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